Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | BIOCARTA_CASPASE CASCADE IN APOPTOSIS |
| Enrichment Score (ES) | -0.7323962 |
| Normalized Enrichment Score (NES) | -1.6480404 |
| Nominal p-value | 0.014644352 |
| FDR q-value | 0.4406379 |
| FWER p-Value | 0.959 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LMNA | 1421654_a_at 1425472_a_at 1426868_x_at 1452212_at 1457670_s_at | 4508 | 0.181 | -0.1851 | No | ||
| 2 | APAF1 | 1450223_at | 5923 | 0.123 | -0.2356 | No | ||
| 3 | PRF1 | 1451862_a_at | 7162 | 0.088 | -0.2821 | No | ||
| 4 | CASP4 | 1449591_at | 8204 | 0.063 | -0.3224 | No | ||
| 5 | GZMB | 1419060_at | 10335 | 0.017 | -0.4177 | No | ||
| 6 | CASP1 | 1449265_at | 10912 | 0.006 | -0.4433 | No | ||
| 7 | BIRC2 | 1418854_at | 11300 | -0.002 | -0.4606 | No | ||
| 8 | PARP1 | 1422502_at 1422503_s_at 1435368_a_at 1443573_at | 12409 | -0.026 | -0.5083 | No | ||
| 9 | BIRC3 | 1421392_a_at 1425223_at | 12618 | -0.030 | -0.5143 | No | ||
| 10 | LMNB1 | 1423520_at 1423521_at | 14952 | -0.087 | -0.6109 | No | ||
| 11 | DFFB | 1421229_at 1437051_at | 15300 | -0.097 | -0.6156 | No | ||
| 12 | CASP8 | 1424552_at | 17860 | -0.205 | -0.7091 | Yes | ||
| 13 | LMNB2 | 1451849_a_at | 17948 | -0.211 | -0.6891 | Yes | ||
| 14 | SREBF1 | 1426690_a_at | 18399 | -0.246 | -0.6817 | Yes | ||
| 15 | CASP3 | 1426165_a_at 1430192_at 1449839_at | 18928 | -0.295 | -0.6722 | Yes | ||
| 16 | CASP6 | 1415995_at 1458715_at | 19677 | -0.403 | -0.6606 | Yes | ||
| 17 | CASP2 | 1448165_at | 19991 | -0.466 | -0.6219 | Yes | ||
| 18 | ARHGDIB | 1426454_at | 20297 | -0.551 | -0.5732 | Yes | ||
| 19 | CASP9 | 1426125_a_at 1437537_at 1457816_at | 21386 | -1.311 | -0.4739 | Yes | ||
| 20 | CASP7 | 1426062_a_at 1448659_at | 21603 | -1.778 | -0.2819 | Yes | ||
| 21 | DFFA | 1450885_at 1457564_at | 21788 | -2.615 | 0.0068 | Yes |
